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Hormonal Medications Used To Treat Endometriosis

Hormonal Medications Used to Treat Endometriosis

Endometriosis is a female reproductive disease characterised by chronic pelvic pain, whether during menstrual cycles or sexual activities, as well as by irregular internal bleeding and infertility. Luckily, there are many ways to detect and treat it. More recently, however, interest in hormonal medications for endometriosis is rising. If you’re also one of those looking to treat the disorder through hormone-centred drugs, then below is a list of them for your convenience.

Dienogest

Dienogest is a progestin medication containing a particular type of progestogen that has low to moderate antigonadotropic traits as well as strong endometrial capabilities. Though typically used in birth control pills and in menopausal hormone therapies to alleviate heavy periods, it can also help treat endometriosis. However, you should take note that it sometimes incurs side effects like nausea, headaches, breast tenderness, and irregular menstrual bleeding. Dienogest is widely available in drug stores under brand names like Qlaira, Natazia, Visanne, and Dinagest. It is orally taken, and it’s often given in hormonal therapies.

Leuprorelin

Leuprorelin is a manufactured version of the gonadotropin-releasing hormones (GnRH) modulators, which help activate your body’s GnRH receptors to stimulate its growth, puberty maturation, and reproductive processes. Aside from treating endometriosis, it can also be used to battle diseases like breast cancer and uterine fibroids. It also serves as a medication for prostate cancer and specific other male reproductive problems due to its ability to decrease testosterone production, although an initial spike in T levels is known to occur during the drug’s first administration. It’s recommended by many doctors who specialise in bioidentical hormone replacement therapy for men. Common side effects include headaches, hot flashes, trouble sleeping, and unstable mood.

Danazol

Danazol is characterised as a suppressive steroid, with weak androgen, progestogen, anti-gonadotropin, and steroidogenesis inhibitor levels as well as functional anti-oestrogen capabilities. Sold under brand names like Danocrine and Lozana, it is an oral medicine used to treat reproductive disorders like endometriosis, hereditary angioedema, and fibrocystic breast disease. However, usage of this drug is limited due to the masculinizing side effects it produces, including excessive hair growth, acne, and voice deepening.

Gestrinone

Gestrinone is also a suppressive steroid like danazol, used as a birth control medication as well as to fight endometriosis, heavy menstrual bleeding, and uterine fibroids. Unlike other medicines, though, it is not formulated to work with other drugs. Its side effects include estrogen deficiency, menstrual abnormalities, and (again like danazol) symptoms of masculinization like acne and increased hair growth. Sold under brand names like Nemestran and Dimetrose, it can be taken orally or intravaginally.

Aromatase Inhibitors

Aromatase inhibitors inhibit testosterone conversion into oestrogen, thus blocking oestrogen production in the body. Although technically not a drug against endometriosis, as it serves as a medication for breast cancer in women and gynaecomastia in men, it’s fast becoming a topic of interest among researchers who are trying to discover new cures for the disease. Indeed, some of the limited quality studies made by these scientists are showing very promising results, although there are still side effects. Examples of these drugs include anastrozole and letrozole, both of which are used to treat breast cancer.

Hormonal Contraception Pills

Hormonal contraception pills are usually the most commonly prescribed treatment for endometriosis because they are generally inexpensive, easy to use, and long-lasting. Plus, they can reduce the risk of ovarian and endometrial cancer. In any case, many birth control medications are known to decrease the menstrual pain that’s often associated with endometriosis, primarily due to its ability to reduce (if not eliminate it altogether) the menstrual flow in the uterus and provide additional oestrogen support. Hormonal contraception pills are just part of this drug group.

Consult Your Gynaecologist First

If you have endometriosis, then these drugs will help you a lot. But as you may probably know by now, taking any of these medications have side effects that can be annoying if not downright debilitating. So better talk to your gynaecologist first.

About Hodge:

Though not a medical professional, Hodge Racter knows a lot about testosterone replacement therapy, having undergone the procedure himself. Today, he remains spry and energetic despite his age, and when he’s not doing freelance work, he’s having quality time with his wife and two dogs.

Image courtesy: Pixabay.com

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